What is Butyrate?
Butyrate is a four-carbon short-chain fatty acid that naturally occurs in certain foods and is produced by gut bacteria during the fermentation of dietary fiber.
Butyrate is a short chain fatty acid known for its role in promoting gut health. The ingredient is a primary energy source for colonocytes, the cells that line the colon and helps maintain the integrity of the gut barrier.
Butyrate can modulate immune function by influencing both innate and adaptive immune responses. The ingredient has been shown to regulate the production of cytokines to help maintain immune homeostasis.
BIOMEnd is engineered as L-lysine butyrate and is tasteless and highly soluble for easy formulation across a variety of supplement formats including powders, capsules, gummies, and more. BIOMEnd’s superior form allows for complete solubility in a liquid
solution and ensures consistent dispersion and distribution setting it apart from its competitors.
Supports Gut and Digestive Health
Supports a Healthy Microbiome
Promotes GLP-1 production to support appetite control
Promotes nutrient absorption in the gut
Although BIOMEnd™ is organoleptically tasteless and does not affect the flavor of a formulation, it may retain a faint odor due to the inherent volatility of butyric acid. This odor is significantly milder than traditional sources like sodium butyrate or tributyrin. In capsule products, odor can be effectively masked using scented desiccants (e.g., vanilla or mint). In powdered applications, pairing BIOMEnd™ with flavor systems that feature chocolate, vanilla, strawberry, peanut butter, or mint helps neutralize any residual aroma and enhances the sensory experience.
In a pharmacokinetic comparison study, lysine butyrate (BIOMEnd™) showed a Cmax over 5x greater and an AUC 1.75x higher than tributyrin, with a significantly faster Tmax (20 min vs. 51.5 min) (La Monica et al., 2025). These metrics reflect superior systemic uptake and faster biological action, making BIOMEnd™ ideal for applications targeting the gut-brain axis, energy, and mood regulation.
Yes. BIOMEnd™ is the first butyrate source designed for ready-to-mix powders, gummies, and functional foods. Its tasteless and free-flowing properties make it highly versatile—unlike traditional butyrates, which require encapsulation due to odor and palatability concerns.
DISCLAIMER: The description, content, and data contained in this website is based on our present knowledge and experience and may be used at your discretion and risk. It, in no way, relieves from carrying out your own internal procedures and tests. NutraShure assumes no liability in connection with your product and/or its use. It is your responsibility to comply with all applicable laws and regulations as well as observe any third-party rights.
† These Statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent and disease.
